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Genomics & genetics for crop improvement, food security, biodiversity, and genome evolution research

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Lab of Pat Heslop-Harrison & Trude Schwarzacher, University of Leicester UK phh4(a)le.ac.uk

Molecular cytogenetics homepage

Our research on genome evolution in agricultural species provides data-driven insights and evidence-based decision-making for breeding and crop improvement and biodiversity conservation or exploitation. It supports policy and practices, with fundamental implications for genome evolution. Work is at University of Leicester and Chinese Academy of Sciences.

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Latest publications and news
Our 2022/2023 whole genome assemblies cover Avena, oats, and in the Banana family species Ensete glaucum and Musa beccarii.. We have studied the chloroplast genomes in apomictic Taraxacum (dandelions). A 2023 publication considers the role of polyploidy or whole genome duplication in ecology and evolution. We had 2023 talk on flax/linseed/Linum genomic diversity.

Publications

New project on
Diversity, Molecular Cytogenetics and Genomics of enset.

  • Conferences including IBCXIX Shenzhen here:
    Conferences

    Teaching material is linked here

    TEACHING

    And social media posts including YouTube here

    SOCIAL
  • Here's why what we do matters

    We have fundamental objectives of understanding genome evolution and biodiversity, impacting agricultural sustainability and ensuring food security. We focuss around crop plants and farm animals at DNA, chromosome and genome levels. We use microscopy, bioinformatics, in situ hybridization, molecular genetics, and systems biology to gain a comprehensive understanding of fundamental processes related to chromosomes, polyploidy, and DNA sequence evolution. We evaluate the environmental outcomes of agricultural practices and assess their consequences, including their economic and social impacts. Leveraging the insights from our research allows improved agricultural genetics.
    RESEARCH

    People, collaborators, editing and teaching

    The group includes PIs, postdoctoral, PhD & project researchers, sabbatical visitors and a part time technician. Our lab is involved in reviewing and editing many journals, including Annals of Botany, Genome, Plant Reproduction and Theoretical and Applied Genetics. We also advise and review national (including REF sub-panel) and international laboratories and programmes. We give undergraduate and advanced courses in Leicester and internationally. Pat Heslop-Harrison is a Professor in University of Leicester (80%) and PI in the South China Botanical Garden, Chinese Academy of Sciences.

    PEOPLE ...

    Our publications, conferences, press and social media

    We have an active publication programme. Titles of recent publications are listed here, or available from Pubmed. www.MolCyt.org contains abstracts and links from 2012 while publications from earlier are here (including at the John Innes Centre JIC, Norwich and Plant Breeding Institute PBI, Cambridge). Information about talks, interviews and other outputs is here.


    Publications
     
    Recent Publications
    Tweets from @PatHH1
    ..
      Recent publications 2022/3
    388. Liu Q, Schwarzacher T, Heslop-Harrison JS. 2023. Polyploidy: its consequences and enabling role in plant diversification and evolution. Annals of Botany 131: 1-9. https://doi.org/10.1093/aob/mcac132.

    387. Tomaszewska P, Schwarzacher T, Heslop-Harrison JS. 2022. Oat chromosome and genome evolution defined by widespread terminal intergenomic translocations in polyploids. Frontiers in Plant Science 13:1026364. https://doi.org/10.3389/fpls.2022.1026364.

    386. Droc G, Martin G, Guignon V, Summo M, Sempéré G, Durant E, Soriano A, Baurens F-C, Cenci A, Breton C, Shah T, Aury J-M, Ge X-J, Heslop Harrison P, Yahiaoui N, D’Hont A, Rouard M. 2022. The Banana Genome Hub: a community database for genomics in the Musaceae. Horticulture Research 9: uhac221. https://doi.org/10.1093/hr/uhac221.

    385. Rathore P, Schwarzacher T, Heslop-Harrison JP, Bhat V, Tomaszewska P. 2022. The repetitive DNA sequence landscape and DNA methylation in chromosomes of an apomictic tropical forage grass, Cenchrus ciliaris. Frontiers in Plant Science 13: 952968. https://doi.org/10.3389/fpls.2022.952968.

    384. Biswas MK, Schwarzacher T, Heslop-Harrison JS. 2022. Large scale genome analysis: genome sequences, chromosomal reorganization, and repetitive DNA in Brassica juncea and relatives. In The Brassica juncea Genome eds Chittaranjan Kole, Trilochan Mohapatra. pp. 269-281. Springer. https://doi.org/10.1007/978-3-030-91507-0_15.

    383. Mustafa SI, Heslop-Harrison JS, Schwarzacher T. 2022. The complete mitochondrial genome from Iraqi Meriz goats and the maternal lineage using whole genome sequencing data. Iranian Journal of Applied Animal Science Jun 1;12(2):321-8. https://journals.iau.ir/article_691854.html.
    Tweets by Pathh1

    Contacting us and directions to visit us

    Phone: +44/0 794 603 450-two-
    Email: phh(a)molcyt.org

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    Some research

    • Banana genomics
    • Drosophila repeated DNA
    • Pararetroviruses
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