Molecules That Move
of the characteristics that distinguishes living from non-living things is
co-ordinate movement, yet at molecular level the components of all materials
undergo frantic vibrations and collisions many millions of times per second.
his Inaugural Lecture University of Leicester Professor of Physical Biochemistry
Clive R Bagshaw will explore how these frenetic molecular motions are harnessed
in nature to result in such co-ordinated movement as muscle contraction.
Bagshaw commented: “Our knowledge of
these events is based on more than 100 years of studying a core protein, myosin,
from a biological, chemical and physical angle.
My presentation will focus on the methods that I have used to define
movements within the myosin molecule and how these may impart net motion
relative to a partner protein, actin.”
will also discuss the extensive use that has been made of the phenomenon of
fluorescence, which in recent years has enabled the behaviour of single myosin
molecules to be studied.
added: “The complexity of these
molecular machines reveals that there is ample ‘room at the bottom’ for
developments in nanotechnology.” His research has been sponsored primarily by
the Biotechnology and Biological Sciences Research Council, The Wellcome Trust
and The Royal Society.
Clive R Bagshaw’s Inaugural Lecture, entitled Molecules
that Move will take place on Tuesday, May 6, 2003 at 5.30 pm in Lecture
Theatre 1, Ken Edwards Building, University of Leicester main campus. It is open to the public and free.
NOTE TO EDITORS:
More information is available from Professor Clive R Bagshaw, Professor
of Physical Biochemistry, University of Leicester Department of Biochemistry,
tel 0116 252 3454, fax 0116 252 3369, email email@example.com
This document has been approved by the head of department or section.