NON-HODGKIN'S LYMPHOMA /
ACUTE LYMPHOBLASTIC LEUKAEMIA

Non-Hodgkin's lymphoma
Both Hodgkin's disease and non-Hodgkin's lymphoma are malignancies of the immune system that affect the lymph nodes. Classification between the two is based on histological appearance: Hodgkins lymphomas classically contain Reed-Sternberg cells which are large binucleated cells. The majority of non-Hodgkins lymphomas are malignant tumours derived from a type of white blood cell (B-cell lymphocytes), and there is often some bone marrow involvement too - if the percentage of lymphoblasts (immature lymphocytes) in the marrow is greater than 25%, then the lymphoma becomes...

Acute Lymphoblastic Leukaemia
Leukaemias are a group of bone marrow malignancies in which there is overproduction of abnormal, immature lymphocytes, which are called lymphoblasts. This overproduction suppresses production of normal healthy lymphocytes and other blood cells, which means the patients immune system is compromised and makes them more susceptible to infections...

So...
The basic distinction between the two is that non-Hodgkin's lymphoma starts in the lymph nodes and may affect the bone marrow, wheras Acute Lymphoblastic Leukaemia starts in the bone marrow and may then spread to the lymph nodes.

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